An autoimmune condition called scleroderma results in inflammation and fibrosis, or thickening, of the skin and other bodily tissues. Scleroderma develops when an immune reaction misleads tissues into believing they are damaged, resulting in inflammation and excessive production of collagen by the body. Tight, hard spots on your skin are caused by an excess of collagen in your skin and other tissues. Numerous bodily systems may be impacted by scleroderma. Numerous bodily systems are impacted by systemic sclerosis, commonly known as systemic scleroderma. This is a more severe form of scleroderma that can harm internal organs like the kidneys, lungs, and heart as well as blood vessels. There is no recognized cause of scleroderma.
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